书目名称 | HIV Interactions with Host Cell Proteins |
编辑 | Paul Spearman,Eric O. Freed |
视频video | |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | The study of viruses necessarily involves dissecting the intimate details of cellular pathways. Viruses have often been employed as tools in studying cellular pathways, as was done by early retrovirologists such as Peyton Rous in attempting to understand the mechanism of cellular transformation and oncogenesis. On the other side of the coin, virologists seek to de?ne those cellular elements interacting intimatelywiththeir virus ofinterestinorder to better understand viral replication itself, and in some cases to develop antiviral strategies. It is in the intersection of virology and cell biology that many of us ?nd the most rewarding aspects of our research. When a new discovery yields insights into basic cellular mechanisms and presents new targets for int- vention to ?ght a serious pathogen, the impact can be high and the excitement intense. HIV has been no exception to the rule that viruses reveal many basic aspects of cellular biology. In recent years, in part because of the importance of HIV as a major cause of human suffering, numerous cellular processes have been elucidated through work on processes or proteins of this human retrovirus. The excitement in this ?eld is especia |
出版日期 | Book 2009 |
关键词 | AIDS; HIV; HIV-1 replication; cellular vesicular trafficking; imaging; retroviral replication; tetherin; te |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-02175-6 |
isbn_softcover | 978-3-642-26182-4 |
isbn_ebook | 978-3-642-02175-6Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |