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楼主: deduce
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Michael Baur,Jan Kantowsky,Axel Schultesleep disorder disturbing nocturnal sleep (e.g., obstructive sleep apnea), insufficient sleep, and/or circadian dysrhythmias. EDS represents the common background feature of these disorders which have different pathophysiology and clinical features. Due to dysfunction of the central nervous system,
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https://doi.org/10.1007/978-3-8349-8380-0ly in physiology and behavior. At the molecular level, the circadian clock consists of a cell-autonomous transcription-translation feedback loop that maintains a 24-h cycle of gene expression. A master clock in the brain serves as a pacemaker for molecular clocks throughout the body to coordinate ci
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Introduction,nsufficient quantity and quality of sleep are steadily increasing. There is substantial evidence that there are negative consequences to habitual “short sleep,” defined as sleeping <6 h per night [1]. There appears to be a particularly strong relationship between short sleep and the health span, in
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The Genetics of Sleep in eep phenotypes to genomic variants and genes are discussed. Also presented are genetic approaches to localize sleep circuitry in the brain and peripheral tissues. Additionally, the chapter explores the role of physiological and environmental context on sleep, including aging, immune response, metabo
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