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发表于 2025-3-21 18:44:29 | 显示全部楼层 |阅读模式
书目名称Guide to Targeted Therapies: EGFR mutations in NSCLC
编辑Federico Cappuzzo
视频video
图书封面Titlebook: ;
出版日期Book 2014
版次1
doihttps://doi.org/10.1007/978-3-319-03059-3
isbn_softcover978-3-319-03058-6
isbn_ebook978-3-319-03059-3
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The Human Epidermal Growth Factor Receptor (HER) Family: Structure and Function,r 1 [HER1]), HER2 (c-ErbB-2), HER3 (c-ErbB-3), and HER4 (c-ErbB-4). These proteins are coded by distinct genes that are expressed on chromosomes 7, 17, 12, and 2, respectively. Although specific soluble ligands have been identified for the extracellular domains of EGFR, HER3, and HER4, no ligand has been identified for HER2.
发表于 2025-3-23 09:34:25 | 显示全部楼层
Conclusions,. In patients with non-small cell lung cancer (NSCLC) it is now mandatory to evaluate . (.) mutation status before treatment choice and EGFR tyrosine kinase inhibitors (TKIs) are the optimal option in the patients harboring activating . mutations.
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