Titlebook: ;

粗野

Supervision: Applying Action Alternatives,odium and calcium through the cGMP-gated ion channels. The consequence of this event is 2-fold: first, the decrease in the inward sodium current plays the major role in an abrupt hyperpolarization of the cellular membrane; secondly, the decrease in the Ca.influx diminishes the free intracellular Ca.

哎呦

贫困

D. Wild,K. Eckhardt,E. Gocke,M. T. Kingeurotransmission. The prosthetic heme group of the enzyme acts as the NO sensor, and binding of NO induces conformational changes leading to an up to 200-fold activation of the enzyme. The unexpected fast dissociation half-life of NO of a few seconds is fast enough to account for the deactivation of

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https://doi.org/10.1007/b137958ggregation and neural signalling) through the accumulation of cGMP and the engagement of various downstream targets, such as protein kinases and ion channels. Until recently, our understanding of sGC functioning has been derived exclusively from studies of the enzyme in tissue homogenates or in its

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雄辩

Michael A. Pereira,Richard J. Bulls of GCAP-1 in ROS-GC1. In addition to GCAPs several other proteins including aktin, tubulin, a glutamic-acid-rich protein and a GTPase accelerating protein (RGS9) were found to interact with ROS-GC1 and probably form a multiprotein complex. (Mol Cell Biochem .: 97–106,2002)

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perjury

A novel role of RGS9: Inhibition of retinal guanylyl cyclase,a.-mediated, indirect connection. This article summarizes our studies strongly suggesting that RGS9-1 is directly involved in the cooperative action of PDE and retGC, and that this ingenious mechanism plays an important role in tuning of cGMP concentration in photoreceptors. (Mol Cell Biochem .: 125–128, 2002)