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发表于 2025-3-26 21:45:23 | 显示全部楼层
CVB-Induced Pancreatitis and Alterations in Gene Expressions of the pancreas and heart. Chronic inflammatory diseases are of major clinical concern, since they predispose affected individuals to cancer. For example, chronic pancreatitis, which can develop from acute pancreatitis, is a major risk factor for pancreatic cancer, a disease with an exceedingly po
发表于 2025-3-27 02:06:49 | 显示全部楼层
The CVB and Etiology of Type 1 Diabetest environmental factors are involved in disease development. The most often cited environmental agents implicated as initiators of T1D are the human enteroviruses, in particular the group B coxsackieviruses (CVB). Although the connection between the CVB and T1D has not been firmly established, signi
发表于 2025-3-27 08:47:24 | 显示全部楼层
发表于 2025-3-27 13:25:32 | 显示全部楼层
Autoimmunity in Coxsackievirus Infectionve cross-reactions. Sometimes these virus-triggered immune responses progress to a pathogenic autoimmunity to form autoimmune disease. To delineate the mechanisms determining induction of autoimmune disease, we have investigated in detail a model of autoimmune myocarditis induced in genetically susc
发表于 2025-3-27 14:39:09 | 显示全部楼层
发表于 2025-3-27 19:34:33 | 显示全部楼层
Mildred Trotter,Barbara B. Hixonand random drift acting on heterogeneous mutant spectra. Direct experimental evidence indicates that high mutation rates and complex mutant spectra can serve for the adaptation of enteroviruses to complex environments. Studies with the RNA-dependent RNA polymerase of picornaviruses suggest that mult
发表于 2025-3-27 22:34:22 | 显示全部楼层
Yusuf Cem Kaplan,Hilal Erol-Coskuncapsid sequence alignments and virion structures allows correlation of capsid diversity with surface features, such as loops, the receptor canyon, and antigenic sites. Pairwise sequence comparisons and phylogenetic analyses can be used to rapidly identify and classify enteroviruses. Enteroviruses ar
发表于 2025-3-28 02:57:01 | 显示全部楼层
https://doi.org/10.1007/978-3-642-81302-3r than through examination of naturally occurring virus strains. The CVB replicate well in a variety of different murine and human cell cultures, making them excellent viruses with which to engage the problem of how the host environment interacts with specific viral genetics to promote varying effic
发表于 2025-3-28 06:59:02 | 显示全部楼层
https://doi.org/10.1007/978-1-4939-1118-9ulin superfamily protein with two extracellular Ig-like domains, a single membrane-spanning sequence, and a significant cytoplasmic domain. It is structurally and functionally similar to the junctional adhesion molecules. The amino terminal domain, distal from the membrane, has been structurally cha
发表于 2025-3-28 13:59:21 | 显示全部楼层
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