书目名称 | Glucose-sensing Receptor in Pancreatic Beta-cells | 编辑 | Itaru Kojima | 视频video | | 概述 | The first book to review the glucose-sensing receptor in pancreatic beta-cells.Helps readers understand the pathophysiology of diabetes.Reviews the complex history of the glucose-sensing machinery in | 图书封面 |  | 描述 | .Since the 1970s, there has been much discussion about the “glucoreceptor” and “substrate site” and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.”.This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells..The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: “glucoreceptor theory”.. .Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes. . | 出版日期 | Book 2018 | 关键词 | Insulin secretion; Diabetes; Sweet Taste Receptor; Glucoreceptor; Metabolism | 版次 | 1 | doi | https://doi.org/10.1007/978-981-13-0002-8 | isbn_ebook | 978-981-13-0002-8 | copyright | Springer Nature Singapore Pte Ltd. 2018 |
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