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Titlebook: Glucose-sensing Receptor in Pancreatic Beta-cells; Itaru Kojima Book 2018 Springer Nature Singapore Pte Ltd. 2018 Insulin secretion.Diabet

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书目名称Glucose-sensing Receptor in Pancreatic Beta-cells
编辑Itaru Kojima
视频video
概述The first book to review the glucose-sensing receptor in pancreatic beta-cells.Helps readers understand the pathophysiology of diabetes.Reviews the complex history of the glucose-sensing machinery in
图书封面Titlebook: Glucose-sensing Receptor in Pancreatic Beta-cells;  Itaru Kojima Book 2018 Springer Nature Singapore Pte Ltd. 2018 Insulin secretion.Diabet
描述.Since the 1970s, there has been much discussion about the “glucoreceptor” and “substrate site” and which of these two is the dominant theory, but new findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.”.This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells..The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapters present the history of this field and explain the hypothesis of insulin secretion mechanisms: “glucoreceptor theory”.. .Subsequent chapters examine the function and activity of the glucose-sensing receptor in pancreatic beta-cells, such as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor and glucose metabolism in pancreatic beta-cells, new insights into the pathophysiology of diabetes, and learn about new targets for the treatment of diabetes. .
出版日期Book 2018
关键词Insulin secretion; Diabetes; Sweet Taste Receptor; Glucoreceptor; Metabolism
版次1
doihttps://doi.org/10.1007/978-981-13-0002-8
isbn_ebook978-981-13-0002-8
copyrightSpringer Nature Singapore Pte Ltd. 2018
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,The Role of the Glucose-Sensing Receptor in Glucose-Induced Insulin Secretion in Pancreatic β-Cellscked by an inhibitor of T1R3 or deletion of the T1R3 gene, glucose-induced insulin secretion (GIIS) is significantly reduced. In perifusion system, both first and second phases of GIIS are attenuated by the inhibition of the glucose-sensing receptor. Collectively, the glucose-sensing receptor is inv
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https://doi.org/10.1007/978-1-4471-3089-5cked by an inhibitor of T1R3 or deletion of the T1R3 gene, glucose-induced insulin secretion (GIIS) is significantly reduced. In perifusion system, both first and second phases of GIIS are attenuated by the inhibition of the glucose-sensing receptor. Collectively, the glucose-sensing receptor is inv
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