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Titlebook: Glucagon I; Pierre J. Lefèbvre (Professor of Medicine, Guest P Book 1983 Springer-Verlag Berlin Heidelberg 1983 Drogen.Glucagon.Hormone.Hy

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书目名称Glucagon I
编辑Pierre J. Lefèbvre (Professor of Medicine, Guest P
视频video
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Glucagon I;  Pierre J. Lefèbvre (Professor of Medicine, Guest P Book 1983 Springer-Verlag Berlin Heidelberg 1983 Drogen.Glucagon.Hormone.Hy
描述The Editorial Board of the Handbook of Experimental Pharmacology apparently did not hurry in suggesting production of a volume on glucagon since the present opus is number sixty-six in the series. This fact is even more striking if we consider that 34 volumes published over about eight years will separate the books on glucagon from those on insulin on library shelves, whereas only a few microns separate the cells manufacturing these two polypeptides within the islets of Langerhans in the pancreas! Numerous factors have probably caused this dicrimination; four of them are: First, insulin deficiency or resistance is the cause of one of the most serious and distressing diseases, diabetes mellitus, which affects millions of people, whereas glucagon deficiency is apparently an extremely rare disorder, for which detailed reports are published of individual cases whenever they occur. Second, since its discovery in 1921 by BANTING and BEST, insulin has been irreplaceable for the treatment of the most severe forms of diabetes, whereas, in contrast, glucagon was until recently considered a relatively minor therapeutic agent. Third, whereas insulin is a compound which has been well characteri
出版日期Book 1983
关键词Drogen; Glucagon; Hormone; Hypophyse; Insulin; Prostaglandin; Sepsis; antibody; antigen; chemistry; chromatogr
版次1
doihttps://doi.org/10.1007/978-3-642-68866-9
isbn_softcover978-3-642-68868-3
isbn_ebook978-3-642-68866-9Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1983
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Glucagon- and Glicentin-Producing Cells M. 1972; W. and V. 1977), this islet cell type has not received as much attention as the insulin-producing B-cell. However, in the last decade, a mounting interest in A-cell structure and function has partially bridged the gap. Interest has been built around the application of different new investi
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Ontogeny and Phylogeny of the Glucagon Cellarch on the gastroenteropancreatic (GEP) neuroendocrine system has undergone an explosively rapid progress, making several statements in that review obsolete and even false. The reason is that, to a great extent, they were based on observations made by means of silver staining techniques (G. and W.
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Glucagon, Glicentin, and Related Peptidesract of the dog contains hyperglycemic factors (M. and S. 1964), and that oral glucose increases plasma GLI in humans (S. et al. 1965) laid the foundation for the concept that the intestine contains peptides which differ from glucagon, but which have certain immunochemical and biologic properties in
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Glucagon Preparationsume by B. (Chap. 1) and B. (Chap. 3) respectively. As emphasized by B. (Chap. 1), the primary structures of porcine, bovine, and human glucagon are identical, but different primary structures have been reported for guinea pig, avian, and piscine glucagons. The present chapter will summarize the prod
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