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Titlebook: Glioma Cell Biology; Aleksi Sedo,Rolf Mentlein Book 2014 Springer-Verlag Wien 2014 Brain.Glioblastoma.Glioma.Tumor.Tumor Angiogenesis.Tumo

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Hormesis: What it is and Why it Matters,tumor-promoting processes are several auto- and paracrine factors, mostly bioactive peptides. Among them, distinct neuropeptides, chemokines, growth factors, and cytokines play a prominent role. Since receptors for neuropeptides are often overexpressed on glioma cells, derivatives are increasingly u
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https://doi.org/10.1007/978-3-662-12026-2ctors. For example, GBM stem cells (GSCs) home to perivascular niches and invasive tumor cells commonly disperse through the brain microenvironment via extracellular matrix (ECM)-rich vascular basement membranes. Anti-vascular agents that target angiogenesis, and particularly those involving vascula
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Analgesic Activity of Endorphins,n large part to the expression of multiple factors by tumor cells that inhibit T-cell responses. In addition, glioblastomas are heavily infiltrated with monocytic cells. These cells appear to have become immunosuppressive under the influence of the tumor and share characteristics with myeloid-derive
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https://doi.org/10.1007/978-1-4613-9208-8neuropathological disorders. Clinical and experimental data show that microglia constitute the dominant immune infiltrate in malignant gliomas. The clinical significance of the mononuclear infiltrate in gliomas remains the subject of controversy. Despite accumulation of these immune cells in both lo
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Breast Susceptibility to Carcinogenesisxtracellular matrix (ECM). The brain ECM is a complex structure composed of proteoglycans and glycoproteins of glial and neuronal origin, which is largely based on hyaluronic acid (HA) as central organizing glycosaminoglycan. It is particularly rich in different carbohydrate epitopes and undergoes a
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Prostate Cancer, Androgens, and Estrogenstube, differently from other glial cells of the astrocyte-like, enteric glia, which originate from the neural crest. Cerebral astrocytes interact with other brain cells such as neurons, mediated by cellular contact involving extracellular matrix (ECM) elements and the integrin of astrocytes. Interac
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Cristina Magi-Galluzzi,Angelo M. De Marzo During gliomagenesis, the complex regulation of proteases in transformed and stromal cells is impaired as a result of several factors, and proteases critically contribute to the hallmarks of gliomas. Proteins regulated by proteases include components of the extracellular matrix, local mediators, ce
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