| 书目名称 | Genotoxicity and Carcinogenicity Testing of Pharmaceuticals | | 编辑 | Michael J. Graziano,David Jacobson-Kram | | 视频video | | | 概述 | Provides context and real case studies to help address critical preclinical safety issues.Provides an overview of alternative and emerging genotoxicity and carcinogenicity tests.Written by well recogn | | 图书封面 |  | | 描述 | .This book provides an overview of the nonclinical testing strategies that are used to asses and de-risk the genotoxicity and carcinogenicity properties of human pharmaceuticals. It includes a review of relevant ICH guidelines, numerous case studies where follow-up studies were conducted to further investigate positive findings, and practical considerations for the use of alternative and emerging tests. .With contributions from recognized experts in the pharmaceutical industry and health authorities, this volume presents a balanced view on the interpretation and application of genotoxicity and carcinogenicity regulatory guidances. .Genotoxicity and Carcinogenicity Testing of Pharmaceuticals. is a valuable resource for scientists, regulators, and consultants that are engaged in the conduct, reporting, and review of nonclinical studies. This book will also help academicians better understand and appreciate the complexity of the regulations and breadth of toxicology research that are necessary to support the development and marketing of new drugs. . | | 出版日期 | Book 2015 | | 关键词 | Carcinogenicity; Genotoxicity; Immunomodulators; In Silico Predictive Tests; Regulatory; Tumor Signals | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-22084-0 | | isbn_softcover | 978-3-319-22083-3 | | isbn_ebook | 978-3-319-22084-0 | | copyright | Springer International Publishing Switzerland 2015 |
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发表于 2025-3-21 17:25:52
