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Titlebook: Genotoxicity Assessment; Methods and Protocol Alok Dhawan,Mahima Bajpayee Book 2019Latest edition Springer Science+Business Media, LLC, par

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https://doi.org/10.1007/978-3-322-83243-6offspring as well as in somatic cells for its own survival. To counter these threats posed by DNA damage, cells have evolved a series of highly choreographed mechanisms—collectively defined as the DNA-damage response (DDR)—to sense DNA lesions, signal their presence, and mediate their repair. Thus,
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Genotoxicity Assessment978-1-4939-9646-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
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https://doi.org/10.1007/978-3-531-92737-4and breaks, as well as the presence of alkali labile sites and cross-links. Here we describe protocols for the single-cell gel electrophoresis (Comet assay) in its alkaline (pH > 13), mild alkaline (pH = 12.1) and neutral (pH = 8) versions when applied in marine animals.
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