| 书目名称 | Genomic Instability and Cancer Metastasis |
| 副标题 | Mechanisms, Emerging |
| 编辑 | Chris Maxwell,Cal Roskelley |
| 视频video | http://file.papertrans.cn/383/382898/382898.mp4 |
| 概述 | Connects cancer metastasis with genomic instability in a comprehensive manner.Outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes.Reviews emerging themes and highl |
| 丛书名称 | Cancer Metastasis - Biology and Treatment |
| 图书封面 |  |
| 描述 | Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1 outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas. |
| 出版日期 | Book 2015 |
| 关键词 | Cancer Metastasis; DNA damage response; Genomic instability; Therapeutic approaches; Tumor heterogeneity |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-12136-9 |
| isbn_softcover | 978-3-319-35295-4 |
| isbn_ebook | 978-3-319-12136-9Series ISSN 1568-2102 Series E-ISSN 2215-1648 |
| issn_series | 1568-2102 |
| copyright | Springer International Publishing Switzerland 2015 |
|Archiver|手机版|小黑屋|
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