| 书目名称 | Genomic Imprinting | | 副标题 | An Interdisciplinary | | 编辑 | Rolf Ohlsson | | 视频video | | | 概述 | This is the first book to take an interdisciplinary approach to genomic imprinting | | 丛书名称 | Results and Problems in Cell Differentiation | | 图书封面 |  | | 描述 | The form and function of every living organism on the earth depends on the complex regulation of gene expression. This is carried out by controlling and interdigitating spatial and temporal patterns of gene activity during the life time of eukaryotic organisms. This is most dramatically apparent during early stages of development, when new types of cells and organs are being formed, often during very short time spans. To achieve this, it is vital that developmentally important genes can be kept in inactive or active states which are stably inherited in the soma. Indeed, it is now wellknown that the propen sity for a gene to be transcribed or silenced is stably propagated through many cell generations, even from parent to progeny. This phenomenon constitutes a type of extragenetic or epigenetic memory of cell identity and developmental potential which has been fundamental to the evolution of complex lifeforms, such as the reader of this book. This monograph focuses on a particular aspect of the epigenetic control of gene function: genomic imprinting. This defines a phenomenon where some genes or whole chromosomes can be silenced, activated, or even deleted depending on their paren | | 出版日期 | Book 1999 | | 关键词 | Activation; biology; cancer; chromosome; developmental biology; evolution; gene; gene expression; genetics; g | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-540-69111-2 | | isbn_softcover | 978-3-662-21956-0 | | isbn_ebook | 978-3-540-69111-2Series ISSN 0080-1844 Series E-ISSN 1861-0412 | | issn_series | 0080-1844 | | copyright | Springer-Verlag Berlin Heidelberg 1999 |
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发表于 2025-3-21 18:32:29
