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Titlebook: Genomic Applications in Pathology; George Jabboure Netto,Karen L. Kaul Book 2019Latest edition Springer International Publishing AG, part

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发表于 2025-3-21 17:57:31 | 显示全部楼层 |阅读模式
书目名称Genomic Applications in Pathology
编辑George Jabboure Netto,Karen L. Kaul
视频video
概述Review the scientific principles underlying next generation genomic technologies and required bioinformatics approaches..Presents implementation roadmaps for various single gene, gene panels, whole ex
图书封面Titlebook: Genomic Applications in Pathology;  George Jabboure Netto,Karen L. Kaul Book 2019Latest edition Springer International Publishing AG, part
描述.  ​The recent advances in genomics are continuing to reshape our approach to diagnostics, prognostics and therapeutics in oncologic and other disorders. A paradigm shift in pharmacogenomics and in the diagnosis of genetic inherited diseases and infectious diseases is unfolding as the result of implementation of next generation genomic technologies. With rapidly growing knowledge and applications driving this revolution, along with significant technologic and cost changes, genomic approaches are becoming the primary methods in many laboratories and for many diseases..  As a result, a plethora of clinical genomic applications have been implemented in diagnostic pathology laboratories, and the applications and demands continue to evolve rapidly. This has created a tremendous need for a comprehensive resource on genomic applications in clinical and anatomic pathology. We believe that our current textbook provides such a resource to practicing molecular pathologists,hematopathologists and other subspecialized pathologists, general pathologists, pathology and other trainees, oncologists, geneticists and a growing spectrum of other clinicians.  With periodic updates and a sufficiently ra
出版日期Book 2019Latest edition
关键词Circulating Tumor Cells; Clinical Genomics; Genomic Medicine; Pharmacogenomics; RNAseq; Sequencing Assays
版次2
doihttps://doi.org/10.1007/978-3-319-96830-8
isbn_ebook978-3-319-96830-8
copyrightSpringer International Publishing AG, part of Springer Nature 2019
The information of publication is updating

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发表于 2025-3-21 20:16:48 | 显示全部楼层
Current Massively Parallel Sequencing Technologies: Platforms and Reporting Considerationsquencing one small (several hundred bp) DNA region at a time, using a specific pair of complementary primers targeted to just that area of interest, the new sequencing platforms utilize a shotgun approach, randomly shearing the entire genome into over 300 million small fragments, sequencing each of
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Emerging Next-Generation Sequencing Technologies number variation, inversions, chromosomal rearrangements], epigenomic, and transcriptional. Long read lengths are required to enable efficient genomic assembly and accurate phasing, and the detection method must produce highly accurate base calls to minimize errors and reduce costly iterative seque
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Circulating Tumor Cells: Enrichment and Genomic Applicationsion of CTCs carries great potential as a tool in cancer patient management and prognostication. Numerous clinical trials on early and metastatic cancer are employing CTCs to evaluate the efficacy of systemic therapy. There is also an increasing interest in using CTCs for detailed molecular and cellu
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Genomic Pathology: Training for New Technologye testing, let alone genomic analysis. Pathologists, given their background in molecular diagnostics and experience directing clinical laboratories, must play a major role in translating genomic technology to patient care. This chapter reviews the significant progress that the pathology community ha
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Clinical Implementation of Next-Generation Sequencing (NGS) Assaysmolecular diagnostic laboratories for various indications. However, laboratory directors need to be prepared for the numerous challenges associated with the implementation of NGS technologies. These include the need to select an appropriate platform based on the purpose of the test, to recruit appro
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