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Titlebook: Genetic Approaches to Coronary Heart Disease and Hypertension; Kare Berg,Victor Bulyzhenkov,Pierre Corvol Conference proceedings 1991 Spri

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Genetic Epidemiology of Ischemic Heart Disease and Arterial Hypertension,Cardiovascular diseases give rise to high morbidity, mortality and infirmity, inflicting heavy social losses on a population (Chazov and Klimov 1980; Oganov 1990). Ischaemic heart disease (IHD) and high blood pressure (HBP) represent a major contribution (Chasov et al. 1986; WHO 1985, 1986).
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978-3-642-76893-4Springer-Verlag Berlin Heidelberg 1991
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Genetic Approaches to Coronary Heart Disease and Hypertension978-3-642-76891-0
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A Population Perspective for Genetics Research and Applications to Control Cardiovascular Disease is strong and due mostly to genetic factors rather than shared family environment. As expected, lipid abnormalities were up to five times more common among coronary siblings than in the general population, but hypertensive siblings also showed up to four times more frequent lipid abnormalities than t
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Gene Mapping in Experimental Hypertension, can be used to study the pathogenesis of hypertension in SHR. To date, we have identified over 70 polymorphic markers that distinguish between the SHR and a normotensive Brown-Norway (BN) strain. Analysis of a large set of recombinant inbred strains derived from the SHR and BN progenitors indicates
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An Overview of the Genetics of Coronary Heart Disease and Its Risk Factors, risk factor variability play a role in atherogenesis. Gene-environment interaction must be important in the etiology of CHD, life style or dietary factors preferentially causing disease in those with a genetic predisposition. Recent evidence indicates that gene-gene interaction also influences risk
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