Titlebook: Gene Therapy in Inflammatory Diseases; Christopher H. Evans,Paul D. Robbins Book 2000 Springer Basel AG 2000 Arthritis.DNA.apoptosis.carti

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书目名称Gene Therapy in Inflammatory Diseases网络公开度学科排名




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书目名称Gene Therapy in Inflammatory Diseases被引频次学科排名




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书目名称Gene Therapy in Inflammatory Diseases年度引用学科排名




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书目名称Gene Therapy in Inflammatory Diseases读者反馈学科排名

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Cartilage erosion in rheumatoid arthritis: studies in SCID mouse model,s. Although genetic factors have been frequently implicated in the pathogenesis of rheumatoid arthritis (RA) [1], and recent reports suggest mutations of tumor suppressor genes to play a role [2], RA is not caused by a specific genetic mutation. Much more likely it is an acquired disorder with a com

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Gene therapy for inflammatory diseases of the salivary glands, hypofunction. As salivary flow is compromised, patients experience oral dryness and difficulties with chewing, swallowing, and speaking. The absence of saliva is usually incompatible with normal oral health; diminished salivary flow results in mucosal inflammation, an increased incidence of oral in

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Gene therapy for management of lupus: Correction of Fas and Fas ligand-induced apoptosis in murine s of tolerance and autoimmune disease. Mutations of . and . are not a common cause of autoimmune disease in humans although a mutation of the . gene has been associated with autoimmune lymphoproliferative syndrome [1–5] and we have described a mutation of the . gene in one patient with systemic lupu

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Gene therapy for multiple sclerosis,allowing the scientific community to consider the treatment of these diseases using new modalities of immunotherapy. The classic forms of therapy for autoimmune disease are directed at general suppression of the immune response. In contrast, newer forms of therapy are aimed at specific cells or cyto

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Gene therapy for type I diabetes mellitus,he insulin-producing β cells of the pancreatic islets of Langerhans. While evidence of a T lymphocyte involvement in the immunopathogenesis of the disease is demonstrated by histologic analysis of the pancreata from children at the onset of the disease and confirmed in animal models like the non-obe

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DNA vaccination as an anti-inflammatory strategy,mmune responses is the key to their efficacy. There are two methods by which vaccines elicit immune responses. The first vaccines developed consisted of live attenuated pathogens which infect the host and stimulate a protective immune response. This includes the smallpox vaccine and the Sabin polio