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Titlebook: Gene Therapy; Principles and Appli Thomas Blankenstein Book 1999 Birkhäuser Verlag 1999 DNA.HIV.bacteria.biotechnology.cancer.gene expressi

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Staatsbürgerrechte und soziale Klassen efficient at transferring genes to a wide variety of target cells . and . and at ex­pressing exogenous genes at a high level [Crystal, 1995; Horwitz, 1996]. After in­fection, the Ad vector expresses the transgene in the nucleus of replicating and non-replicating cells in an epi-chromosomal fashion,
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Nicole Stokes-DuPass,Ramona Frujaer formulations [1–3], although not reaching the efficiencies of viral vectors, have been introduced already into clinical . gene therapies. Nonviral systems are attractive for the following reasons: (i) they may be very flexible with respect to the size of DNA to be transported; (ii) in contrast to
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Nasreen Chowdhory,Biswajit Mohantye techniques, particle-mediated gene transfer (PMT) or “gene gun” has been developed and promising results have been reported in the last few years. Other approaches include use of naked DNA injection (particlularly into muscle), protein coupled DNA to target cellular receptors, calcium phosphate tr
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