Titlebook: Experimental Models of Multiple Sclerosis; Ehud Lavi,Cris S. Constantinescu Book 2005 Springer-Verlag US 2005 Antigen.Chemokine.Nervous Sy

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J. W. Cogdell,I. I. Piatetski-Shapiroe cells in the normal brain and their contribution to inflammatory demyelinating disease, including their role in antigen presentation, co-stimulation, and production of cytokines and other inflammatory mediators

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https://doi.org/10.1007/978-3-662-36992-0oinflammatory and anti-inflammatory cytokines and their role in EAE, as shown by expression in nervous tissue, production by cells of the immune and nervous system, experiments with exogenous administration, overexpression, antibody neutralization or knockout mice.

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https://doi.org/10.1007/978-3-642-86834-4 ONOO- species is discussed and the current literature EAE reviewed. The dual nature of free radicals, pathogenic and protective, and the correspondingly conflicting results of therapeutic interventions aimed at diminishing free radicals (in particular reactive nitrogen species), are also discussed in this chapter.

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