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Titlebook: Erythropoietins, Erythropoietic Factors, and Erythropoiesis; Molecular, Cellular, Steven G. Elliott,Mary Ann Foote,Graham Molineux Book 200

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书目名称Erythropoietins, Erythropoietic Factors, and Erythropoiesis
副标题Molecular, Cellular,
编辑Steven G. Elliott,Mary Ann Foote,Graham Molineux
视频video
概述Covers background and basic science, erythropoiesis-stimulating agents, chapters on the erythropoietin receptor as well as clinical uses of recombinant erythropoietins.Also of interest to clinicians i
丛书名称Milestones in Drug Therapy
图书封面Titlebook: Erythropoietins, Erythropoietic Factors, and Erythropoiesis; Molecular, Cellular, Steven G. Elliott,Mary Ann Foote,Graham Molineux Book 200
描述Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the eryth- poietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as a recombinant protein, much was written about EPO. Although much has been learned and published, new, exciting data are becoming ava- able on almost a daily basis. Erythropoietins and Erythropoiesis: Molecular, Cellular, Preclinical, and Clinical Biology compiles both pertinent historical and very recent research on this molecule and its clinical utility. The book is divided into two sections: Background and Basic Science and Clinical Uses of Recombinant Erythropoietins. To begin, Israels and Israels describe the biology of red cells, the hierarchy of erythropoietic progenitor cells, their development to mature cells, and the effects of endogenous EPO on their development. Foote summarizes the historical interest in, and search for, an erythropoietic factor. Once EPO was identified, cloned, and expressed, the path was set for the study of other aspects of EPO biology both within e- thropoiesis and other cellular systems.
出版日期Book 2009Latest edition
关键词Activation; anemia; biology; biotechnology; blood cell; cancer; cell; cell physiology; erythropoietin; metabo
版次2
doihttps://doi.org/10.1007/978-3-7643-8698-6
isbn_ebook978-3-7643-8698-6Series ISSN 2296-6056 Series E-ISSN 2296-6064
issn_series 2296-6056
copyrightBirkhäuser Basel 2009
The information of publication is updating

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Urbanisation and Urban-Biased Development, finally established in the 19th Century after major advances in biology and chemistry over the preceding two centuries. The description of the blood circulation by William Harvey (1578–1657) in . in 1628 framed the question as to the purpose of moving such large volumes of fluid around the body. Ri
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Olayiwola Abegunrin,Charity Manyerukethe same biologic function as the endogenous product of a human gene located on chromosome 7q22 [., .]. Both the endogenous material (eEPO), and recombinant human glycoprotein (rHuEPO) bind a single receptor (EPOR) [.–.]. Although data from one group challenge this concept by suggesting signaling th
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l mass (anemia). Since polycythemia is often and inconsistently referred to by an alternative term, erythrocytosis, and, as no consensus on usage has been reached, we refer to the individual entities by the term used in the original description. Anemias are far more common than polycythemic states,
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Li Zhang,Junlin Qu,Jing Jie,Nannan Liangthe introduction of recombinant human erythropoietin (rHuEPO), anemia and its sequelae fatigue were treated with red blood cell transfusion, androgen stimulation of red blood cell production, and/or iron supplementation, among other treatments [.]. While effective in increasing red blood cell counts
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China’s Reform and New Urbanizationfive categories: plant, bacterial, yeast, insect, or mammalian. Depending on the type of product that is desired, the features of that product, the intended use of the product, and the preferred method of manufacture, an appropriate host cell can be selected. With the appropriate genetic engineering
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