| 书目名称 | Engineering of Halogenases towards Synthetic Applications |
| 副标题 | Increasing the Therm |
| 编辑 | Hannah Minges |
| 视频video | |
| 概述 | Evolution and investigations on halogenases.Includes supplementary material: |
| 丛书名称 | BestMasters |
| 图书封面 |  |
| 描述 | Hannah Minges focuses on the investigation of two different FAD-dependent halogenases in order to analyze and improve their applicability for chemoenzymatic approaches in chemistry. Owing to beneficial features, like high selectivity and benign reaction conditions, nature’s toolkit for halogenation provides several advantages, whereas conventional chemical strategies require hazardous reagents and suffer from low selectivity. Therefore, enzymatic halogenation arises as promising alternative in the synthesis of valuable chemicals. One project focuses on the generation of a thermostable variant of the tryptophan halogenase Thal by means of directed evolution. The second project deals with the investigation of the marine halogenase Bmp5. This enzyme is of synthetic interest because it preferably introduces bromine into phenol compounds, whereas chlorination cannot take place. . |
| 出版日期 | Book 2017 |
| 关键词 | Thal; Bmp5; Directed Evolution; Enzyme; Biocatalysis |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-658-18410-0 |
| isbn_softcover | 978-3-658-18409-4 |
| isbn_ebook | 978-3-658-18410-0Series ISSN 2625-3577 Series E-ISSN 2625-3615 |
| issn_series | 2625-3577 |
| copyright | Springer Fachmedien Wiesbaden GmbH 2017 |
发表于 2025-3-21 19:41:04
