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Titlebook: Endocrine Therapy of Breast Cancer III; Franco Cavalli Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 breast cancer.ca

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https://doi.org/10.1007/978-3-031-26478-8he many positive comments that we have received following the appearance of the first and second volumes should help us to avoid the danger of starting to consider our endeavour a routine task which has to be completed once a year. I am convinced that this third volume is of high quality and that ou
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https://doi.org/10.1007/978-981-15-2290-1cancer and axillary clearance. Patients with N- disease who were treated in the more recent controlled clinical trials have higher relapse rates than those entered in the earlier series from which our perception of prognosis for these patients has been derived. This could be due to a reporting bias,
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hough another 20% have stable disease. If oestrogen receptor-positive patients are selected for study, tamoxifen produces a 50–60% objective response rate. Nevertheless, about 13% of oestrogen receptor-negative patients can have a response to therapy.
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Control of Follicular Growth and OvulationCompetition of tamoxifen with endogenous oestrogen for binding to oestrogen receptors in the tumour cells attenuates the proliferative action of oestrogens [1,2]. A large body of evidence derived from studies of breast cancer cells ., and of breast tumours in animals supports this simple hypothesis
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The Saddle Back Tamarin and other Tamarins, oestrogens may induce regression of tumour growth. In premenopausal women the ovaries are the main source of oestrogens, while in postmenopausal women oestrogens are mainly derived from extra-ovarian aromatisation of androgenic precursors such as androstenedione [1].
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hough another 20% have stable disease. If oestrogen receptor-positive patients are selected for study, tamoxifen produces a 50–60% objective response rate. Nevertheless, about 13% of oestrogen receptor-negative patients can have a response to therapy.
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