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Titlebook: Emerging Concepts of Tumor Exosome–Mediated Cell-Cell Communication; Huang-Ge Zhang Book 2013 Springer Science+Business Media New York 201

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Immune Modulation of T Cells and Natural Killer Cells by Tumor-Derived Exosomes,ave immunoregulatory properties and contribute to CD8. effector T cell apoptosis, induction/expansion of Treg, and inhibition of NK cell activity. Membrane-associated molecules, such as TGF-b or Fas ligand, are carried by TEX and are responsible for the ability of TEX to regulate peripheral tolerance in patients with cancer.
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https://doi.org/10.1007/978-3-8349-9761-6enesis promotion, stromal remodeling, signaling pathway activation through growth factor/receptor transfer, chemoresistance, and genetic intercellular exchange, tumor exosomes/microvesicles could represent a central mediator of the tumor microenvironment.
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Circulating Cell-derived Vesicles Mediate Tumor Progression,enesis promotion, stromal remodeling, signaling pathway activation through growth factor/receptor transfer, chemoresistance, and genetic intercellular exchange, tumor exosomes/microvesicles could represent a central mediator of the tumor microenvironment.
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The Cell Biology of Exosomes: Historical and Perspectives, outward budding of portions of the plasma membrane, membrane vesicles of 30–100 nm, called exosomes are secreted during fusion of endosomal multivesicular bodies with the cell surface. Exosomes contain membrane and cytosolic components that include proteins, lipids and RNAs. Exosomes from different
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