Titlebook: Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity; Akihiko Yoshimura Book 2017 The Editor(s) (if applicable) and T

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SOCS1: Regulator of T Cells in Autoimmunity and Cancerdriven by inflammatory cytokines. In addition, SOCS1 is critical to maintain the stability of T regulatory cells and control their plasticity to become pathogenic Th17 and Th1 cells under the harmful influence of inflammatory cytokines. SOCS1 also regulates T cell activation by dendritic cells via m

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0070-217X mmunotherapy, and for the therapy of autoimmune diseases...Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike..978-3-319-88684-8978-3-319-68929-6Series ISSN 0070-217X Series E-ISSN 2196-9965

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Book 2017. Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for the therapy of autoimmune diseases...Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike..

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Enrique Ballestero,Carlos Romeromanner. Moreover, the combined expression of LAG-3 and CD49b identifies IL-10-producing Treg cells in mice and humans more specifically. Recently, LAG-3 has gained more attention in the context of immune checkpoints because it believed to be related to T cell tolerance and exhausted T cells that inf

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Multiple Decrement Models in Insurancedences that PD-1 signal is one of the main factors of cancer immune escape in humans. The dramatic efficacy of PD-1 blockade in cancer immunotherapy, promises the control of other immune diseases by PD-1 signal modulation. In this review, we summarize the history of PD-1, subsequent basic studies, a