书目名称 | Electrophysiology of Unconventional Channels and Pores | 编辑 | Anne H. Delcour | 视频video | | 概述 | Timely book on the structure and function of unconventional pores.Covers non-canonical channels and pores of all origins.Written by international experts from different fields | 丛书名称 | Springer Series in Biophysics | 图书封面 |  | 描述 | .This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.. | 出版日期 | Book 2015 | 关键词 | electrophysiology; membrane channels; non-canonical channels; patch clamp; pore forming; unconventional p | 版次 | 1 | doi | https://doi.org/10.1007/978-3-319-20149-8 | isbn_softcover | 978-3-319-37235-8 | isbn_ebook | 978-3-319-20149-8Series ISSN 0932-2353 Series E-ISSN 1868-2561 | issn_series | 0932-2353 | copyright | Springer International Publishing Switzerland 2015 |
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