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Titlebook: Eicosanoids; From Biotechnology t Gian Carlo Folco,Bengt Samuelsson,G. P. Velo Book 1996 Springer Science+Business Media New York 1996 Mamm

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Leukotriene Antagonists and Synthetase Inhibitors; Clinical Applications in the Treatment of Bronch both human subjects and animal models suggest that the abnormalities of asthma are manifestations of airway inflammation that is a key factor even in patients with asthma at a clinically early stage (Laitinen et al., 1993).
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https://doi.org/10.1057/9780230594043ture. Polymorphonuclear granulocytes synthesize nearly exclusively leukotriene B. and eosinophils generate leukotriene C.. Monocytes/macrophages, depending upon their maturation produce both leukotrienes and thromboxane or prostacyclin. In contrast, red blood cells and lymphocytes, devoid of oxygenases cannot generate eicosanoids.
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Developing B2B Social Communitiesxtravasation. Given these differences, it is not unexpected that, although both classes have been demonstrated to elicit their actions through the interaction with specific receptors, the receptors for LTB. are totally different from those for .-LTs and no cross-reactivity has been shown among the two classes.
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Transcellular Biosynthesis of Arachidonic Acid Metabolites: From , Investigations to , Reality,ture. Polymorphonuclear granulocytes synthesize nearly exclusively leukotriene B. and eosinophils generate leukotriene C.. Monocytes/macrophages, depending upon their maturation produce both leukotrienes and thromboxane or prostacyclin. In contrast, red blood cells and lymphocytes, devoid of oxygenases cannot generate eicosanoids.
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Receptors and Second Messengers for ,-Leukotrienes,xtravasation. Given these differences, it is not unexpected that, although both classes have been demonstrated to elicit their actions through the interaction with specific receptors, the receptors for LTB. are totally different from those for .-LTs and no cross-reactivity has been shown among the two classes.
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