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Titlebook: Effects of Nicotine on Biological Systems II; Paul Brian Sydenham Clarke,Maryka Quik,Klaus Thura Book 1995 Springer Science+Business Media

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https://doi.org/10.1007/978-1-4842-4540-8gnant rats with continuous infusions (implanted minipumps), we have been able to separate the contributing variables of hypoxia/ischemia, maternal nutrition and fetal growth retardation from the direct effects of nicotine exerted on developing neurons. Nicotine mimics the natural actions of acetylch
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Advances in Pharmacological Scienceshttp://image.papertrans.cn/e/image/302869.jpg
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Data Warehouse Requirements Engineeringerties, but α8 homomers and native α8 AChRs have lower affinity for α-BTX and higher affinity for small cholinergic ligands than do α7 homomers and α7 AChRs. The high Ca. permeability and rapid desensitization of α7 and α8 AChRs may enable them to participate in unusual synaptic mechanisms.
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Involvement of Nicotine and Its Metabolites in the Pathology of Smoking-Related Diseases: Facts and founded hypotheses how smoking could contribute to the development of these diseases. On the other hand, the constituents of cigarette smoke that might be the causative agents remain to be identified. At present, there is no evidence at all that nicotine — the substance most smokers smoke for — has
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A Cyclophilin-Dependent Mechanism for ,7 Neuronal Nicotinic Acetylcholine Receptor Maturationomodulatory and developmental role. Here we present evidence that the expression of α7 homo-oligomeric receptors in Xenopus oocytes is dependent on the activity of the peptidyl prolyl isomerase (PPIase) cyclophilin. We show further that the expression of the hetero-oligomeric muscle nAChR is devoid
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