Titlebook: Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells; Novel Insights into Cheryl A. Nickerson,Neal R. Pelli

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Principles of Analogue and True Microgravity Bioreactors to Tissue Engineeringeliberate approach, it would have been difficult to advance our understanding of low gravity and low fluid shear environments and their impact on cellular biology. This innovative approach to cell culture and tissue engineering enabled the development of three-dimensional (3-D) organotypic tissue ag

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Microgravity and Microgravity Analogue Studies of Cartilage and Cardiac Tissue Engineering function of our tissues and organs. The ability of engineered tissue constructs to recapitulate some of the critical and physiological functions opened many exciting avenues of research..In this chapter, we discuss representative ground-based analogue and spaceflight studies of tissue engineering r

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Microbial Investigations: Overviewoccupation of the relatively small, closed environments of spacecraft/habitats..Studies of microorganisms in spaceflight analogues and true spaceflight began as simple investigations to understand the basic phenotypic characteristics of microorganisms when cultured in the spaceflight environment. Ho

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Response of , to Spaceflight and Spaceflight Analogue Culture: Implications for Astronaut Health anduggests a conserved response with . serovar Typhimurium (the first pathogen for which this response was observed in both microgravity and microgravity-analogue culture) and .. Besides the importance of these findings for the risk assessment, prevention, and treatment of infectious diseases during sh