| 书目名称 | DNA Replication Control in Microbial Cell Factories | | 编辑 | Monika Glinkowska,Lidia Boss,Grzegorz Wegrzyn | | 视频video | | | 概述 | Unique analysis of the current knowledge on the control of DNA synthesis.Discussion of unexpected discoveries in the field of the control of genetic material replication.Description of links between m | | 丛书名称 | SpringerBriefs in Microbiology | | 图书封面 |  | | 描述 | This work describes the current knowledge of biochemical mechanisms regulating initiation of DNA replication in .Escherichia coli., which focuses on the control of activity of the DnaA protein. Examples of direct linkages between DNA replication and other cellular processes are provided. In addition, similarities of the mechanisms of regulation of DNA replication operating in prokaryotic and eukaryotic cells are identified, and implications for understanding more complex processes, like carcinogenesis are suggested..Studies of recent years provided evidence that regulation of DNA replication in bacteria is more complex than previously anticipated. Multiple layers of control seem to ensure coordination of this process with the increase of cellular mass and the division cycle. Metabolic processes and membrane composition may serve as points where integration of genome replication with growth conditions occurs. It is also likely that coupling of DNA synthesis with cellular metabolism may involve interactions of replication proteins with other macromolecular complexes, responsible for various cellular processes. Thus, the exact set of factors participating in triggering the replicati | | 出版日期 | Book 2015 | | 关键词 | Carcinogenesis; Central carbon metabolism; Coupling of transcription and replication processes; DNA rep | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-319-10533-8 | | isbn_softcover | 978-3-319-10532-1 | | isbn_ebook | 978-3-319-10533-8Series ISSN 2191-5385 Series E-ISSN 2191-5393 | | issn_series | 2191-5385 | | copyright | The Author(s) 2015 |
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发表于 2025-3-21 18:07:09
