Titlebook: Cytokines, Stress, and Depression; Robert Dantzer,Emmanuelle E. Wollman,Raz Yirmiya Book 1999 The Editor(s) (if applicable) and The Author

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CROW

Cytokine Production in Depressed Patients. A concept of an interrelationship between the immune system and the nervous system, i.e. the psychological state, has been suggested before the first studies in psychoneuroimmunology have been conducted. Several authors implicated that mood disturbances may result in an increased susceptibility to

Carcinoma

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Mood and Cognitive Disorders in Cancer Patients Receiving Cytokine Therapyncreasing attention is being paid to the effects of these agents on the central nervous system (CNS). It is now known that cytokine therapy can be associated with the development of cognitive and psychiatric adverse effects that range from subtle impairments of attention and memory undetectable on r

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Mechanisms of the Behavioural Effects of Cytokinesidual typically displays depressed locomotor activity and little or no interest in his physical and social environment. Body care activities are usually absent and ingestive behavior is profoundly depressed despite the increased metabolism that is necessary for the fever response. Since the initial

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Effects of Cytokines on Glucocorticoid Receptor Expression And Function & Felten, 1991; Miller, In Press). Immune cells and tissues express receptors for a wide range of transmitters associated with and regulated by the nervous system including neuro-transmitters, peptides and hormones, and nervous system innervation of lymphoid tissues has been well characterized. Mor

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Effects of Cytokines on Cerebral Neurotransmissiono-pituitary-adrenocortical (HPA) axis. However, extensive work in the past 30 years has indicated that responses also occur in the central nervous system. The major response occurs in noradrenergic (NA) neurons. Most studies have also noted responses in dopaminergic (DA) and serotonergic (5-HT) syst

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Inflammation and Brain Function under Basal Conditions and During Long-Term Elevation of Brain Cortitical (HPA) axis, fever, and sickness behaviour, to promote survival and return of homeostasis. The underlying neurotransmitter responses in the brain, however, still need to be further characterized. Using an . microdialysis method in rats, we have shown that peripheral inflammation (induced by int

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Dynamic Regulation of Proinflammatory Cytokineswide variety of immune cells in response to infection, inflammation, and tissue damage. These proteins have long been recognized as critical communication factors for orchestrating early responses of immune cells to such immune challenges. More recently, it has become accepted that these same proinf

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Cross-Sensitization Between Immune And Non-Immune Stressorsrnal or external milieu but also mechanisms that allow experiences to shape the response to later stimuli. Together with its genetic background, it are the specific experiences and their long lasting consequences that model the individual. Aspects of this can be found in almost all cells and organs,