书目名称 | Cytokines and Pain | 编辑 | Linda R. Watkins,Steven F. Maier | 视频video | http://file.papertrans.cn/243/242644/242644.mp4 | 丛书名称 | Progress in Inflammation Research | 图书封面 |  | 描述 | Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cyto | 出版日期 | Book 1999 | 关键词 | Arthritis; central nervous system; cytokine; growth; health care; inflammation; neoplasm; nervous system; pa | 版次 | 1 | doi | https://doi.org/10.1007/978-3-0348-8749-6 | isbn_softcover | 978-3-0348-9756-3 | isbn_ebook | 978-3-0348-8749-6Series ISSN 1422-7746 Series E-ISSN 2296-4525 | issn_series | 1422-7746 | copyright | Springer Basel AG 1999 |
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