Titlebook: Cytokine Knockouts; Scott K. Durum,Kathrin Muegge Book 19981st edition Springer Science+Business Media New York 1998 Colon.Vivo.cytokine.c

浸软

The IL-2 Deficiency Syndrome,units (for review, . ref. 2): an IL-2 specific a-chain with low binding affinity and no signal-transducing capacity; a (3-chain that is shared with the IL-15 receptor (.) and participates in signaling through its cytoplasmic tail; and the “common” γ-chain (γc) shared by receptors for IL-4, -7, -9, a

Fantasy

MILK

Lymphoid Development and Function in IL-7R-Deficient Mice,rearrangement, and cytokine responsiveness. For example, interleukin-7 (IL-7) was originally identified as a factor produced by bone marrow stromal cells that could support the proliferation of B-cell precursors .. The IL-7 responsive B-lineage cells were clearly defined in vitro using sorted B-cell

incite

CD40 Ligand Knockout Mice,nomas (for review, . ref. .). Its counterstructure, CD40 ligand (CD40L), is a 33-kDa glycoprotein expressed primarily on activated CD4. T-cells, but also found on CD8. T-cells, mast cells, basophils (.), and eosinophils (.). CD40L belongs to the tumor necrosis factor (TNF) superfamily (.), members o

边缘

Physiological, Immunological, and Pathological Functions of Tumor Necrosis Factor (TNF) Revealed by observed a remission of inoperable tumors in some patients after infusion of bacterial toxins .. Unacceptable side effects, however, and a lack of understanding of how these toxins induced hemorrhages in tumors, prevented the further development and application of this treatment. It was more than 6

情感

Cooperation Between the TNF Receptors Demonstrated by TNF Receptor Knockout Mice,f NF-κB, cytotoxicity, tumor necrosis as well as antiviral, inflammatory, and immunoregulatory responses. TNF has been implicated as a central mediator of septic shock as well as graft-vs-host disease, arthritis, and several autoimmune disorders. There are two related TNF molecules, TNFα (tumor necr

乳白光

DEBT

omnibus

外向者