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Titlebook: Children with Differences in Sex Development; Taking a Multidiscip Simmi K. Ratan Textbook 2024 The Editor(s) (if applicable) and The Autho

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Meta-analysis and Current Literature on Gender Dysphoriaxed gonadal dysgenesis or partial androgen insensitivity there is a variable risk of gender dysphoria. In 5-alpha reductase deficiency it is high if they are reared as female. Thus, it is essential to arrive at the diagnosis and also be aware of future risk of gender conflict before assigning sex of rearing in DSD children.
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Gender Identity and Role: Revisiting the Psychosocial Mosaice psychological insights into notions around gender and sexuality. Appreciating the varied socio-cultural nuances of gendering is pivotal for developing a multi-dimensional approach to building psychotherapeutic interventions when dealing with cases of DSD and their caregivers.
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Normal Gonadal Developmentonads in either sex, is dependent on the arrival of the germ cells into the gonadal ridge on the medial side of the intermediate mesoderm. The primordial germ cells for a male fetus carry XY chromosome, while XX chromosome for female fetus. Lateral to the developing gonads and the mesonephric ducts,
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Hormonal Regulation During Gonadal Development or female phenotype at birth. These events are classified as phases of sex determination and sex differentiation. Complex interactions of multiple genes, transcription factors, proteins, and hormones are responsible for these intricate changes. The phase of sex differentiation is chiefly brought ab
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Gender Identity and Role: Revisiting the Psychosocial Mosaiche notions of moving beyond the gender binary, the most contemporary paradigm adopted. A nuanced understanding of gender, especially in the context of sexual development is crucial when handling clinical concerns around the (ab)normalcy around sexual development of children. It intends to render som
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Meta-analysis and Current Literature on Gender Dysphoriaender dysphoria has been reported in some adults with DSD. Appropriate sex assignment of DSD children may help in prevention of development of GID in later life. While the population risk of gender dysphoria is less than 0.5%, among DSD individuals the risk is variable 3–15% as per reported literatu
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