Titlebook: Cyclic Nucleotides in the Nervous System; John Daly Book 1977 Plenum Press, New York 1977 adenosine.biology.brain.communication.experiment

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Introduction,phates. The diverse biological effects of cyclic nucleotides appear to be manifested through activation of protein kinases which specifically phosphorylate enzymes and other functional proteins and thus alter their properties. The specificity and nature of the effects of cyclic nucleotides presumabl

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disrupt

Functional Role of Cyclic Nucleotides,MP-generating systems in neuronal or glial cells i.e., biogenic amines, adenosine, prostaglandin, or depolarizing agents. Antagonists of the stimulatory agents have also been employed to advantage. Similar paradigms have been employed to alter cyclic GMP levels, for example, through the use of dibut

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态学

in health, must ultimately come from the combined efforts of scientists from many disciplines, including biology, chemistry, histology, pathology, physiology, pharmacology, and psychology. Communication between scientists from these various disciplines-vital to the advancement of our understanding o

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Maurici Ruiz,Joana Maria Seguí-Ponstion of neuronal function a formidable task. However, on the molecular level a variety of evidence indicates that the nucleotides, cyclic AMP and cyclic GMP,* are involved in regulatory roles associated with neuronal function. Cyclic AMP regulates prime functions in many other tissues: gluconeogenes