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Titlebook: Current Understanding and Treatment of Gliomas; Jeffrey Raizer,Andrew Parsa Book 2015 Springer International Publishing Switzerland 2015 C

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楼主: Covenant
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Ärztliche Begutachtung von A - Zm supportive care only, radiation therapy (RT) only (most often given in a shortened hypofractionated schedule), temozolomide (TMZ) chemotherapy only, and the combination RT + TMZ, followed by post-RT TMZ as is the current standard of care for younger good performance patients with newly diagnosed GBM.
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Radiation Therapy of Glioblastoma,t tend to be associated with notable toxicity. More recently, re-irradiation strategies employ concurrent use of bevacizumab to limit treatment-related injury while still permitting delivery of meaningful doses. These clinical trials are ongoing and merits of these strategies are not yet clear but a
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Immunotherapy for Malignant Gliomas,osuppression. The mechanisms of immunosuppression are only now being elucidated, but clearly involve a combination of factors including regulatory T cells, tumor-associated PD-L1 expression, and CTLA-4 signaling. Immunomodulatory agents have been developed to combat these immunosuppressive factors a
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Von Nannas Herden zu Helios’ Rindernmutations or fusions in the BRAF gene seen in pilocytic astrocytomas (and gangliogliomas). In oligodendrogliomas, mutations in IDH1 and codeletion of chromosomes 1p and 19q are associated with improved survival with upfront use of combined chemotherapy and radiation, and these tumors also have uniqu
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Von Nannas Herden zu Helios’ Rindernt tend to be associated with notable toxicity. More recently, re-irradiation strategies employ concurrent use of bevacizumab to limit treatment-related injury while still permitting delivery of meaningful doses. These clinical trials are ongoing and merits of these strategies are not yet clear but a
发表于 2025-3-28 12:52:30 | 显示全部楼层
https://doi.org/10.1007/978-3-662-68110-7s. In the CIMP-negative, mainly . wild-type group, MGMT promoter methylation may be used to identify patients who benefit from alkylating chemotherapy. The mutually exclusive ATRX losses and 1p/19q codeletions are used to subcategorize anaplastic tumors with a mixed histology according to microscopi
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