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Titlebook: Current Progress in the Understanding of Secondary Brain Damage from Trauma and Ischemia; Proceedings of the 6 Alexander Baethmann,Nikolaus

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Environmental Influence on Gene Expression and Recovery from Cerebral Ischemia,bstances with potential role in brain plasticity, show different patterns in animals housed in standard and in enriched environment. The functional significance of altered gene expression needs to be evaluated.
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,Glial Cell Swelling — Effect of Hypothermia,uction of the glutamate- or arachidonic acid-induced cell swelling..The results demonstrate that mild hypothermia per se induces glial cell swelling, but simultaneously inhibits cell swelling from acidosis, while not from glutamate-or arachidonic acid.
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,Heparin-Mediated Extracorporeal LDL/Fibrinogen Precipitation —H.E.L.P.-In Coronary and Cerebral Iscs given back to the patient..H.E.L.P.-apheresis has proved to be safe in patients with coronary heart disease and allows a controlled reduction of thrombogenic plasma compounds. It is therefore hoped to be effective also in patients with acute ischemic stroke.
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Challenges in Translating the Efficacy of Neuroprotective Agents in Experimental Models Into Knowleudies of efficacy, in which expectations of effect need to be lower and correspondingly large numbers of patients studied. Recant experience in the evaluation of glutamate NMDA antagonists is reviewed.
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