Titlebook: Crossroads Between Innate and Adaptive Immunity V; Stephen P. Schoenberger,Peter D. Katsikis,Bali Pul Conference proceedings 2015 The Edit

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Stability of Regulatory T Cells Undermined or Endorsed by Different Type-1 Cytokines,aintenance of tissue homeostasis. Various Treg subtypes, normally resident within distinct lymphoid and non-lymphoid tissues, can be recruited and expanded during inflammation, possibly undergoing functional and molecular re-programming. Generally, two processes have been reported in different setti

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Functional Diversity of Human Dendritic Cells,gh not entirely appreciated at first, it is clear that they play a critical role as specialized antigen-presenting cells and essential mediators in shaping immune reactivity and tolerance. Dendritic cells are now recognized as a heterogeneous group of cells in terms of cell-surface markers, anatomic

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,Selective Dependence of Kidney Dendritic Cells on CX3CR1—Implications for Glomerulonephritis Therapnetwork of DCs also spans the kidneys. DCs play a central role in maintenance of organ homeostasis as well as in induction of immune responses against invading pathogens. They can mediate protective or destructive functions in a context-dependent manner..We recently identified CX.CR1 as a kidney-spe

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Mechanisms of Memory T Cell Activation and Effective Immunity,totoxic/CD8.T lymphocytes, which few will further differentiate into long-lived memory cells persisting in the host and exhibiting improved functional characteristics. The current model is that such memory cells can confer rapid host protection upon cognate antigen-mediated activation and direct kil

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