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Titlebook: Covalent Catalysis by Enzymes; Leonard B. Spector Book 1982 Springer-Verlag New York, Inc. 1982 ATP.Alanin.Aspartat.Catalysis.Coenzym.DNA.

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书目名称Covalent Catalysis by Enzymes
编辑Leonard B. Spector
视频videohttp://file.papertrans.cn/240/239187/239187.mp4
图书封面Titlebook: Covalent Catalysis by Enzymes;  Leonard B. Spector Book 1982 Springer-Verlag New York, Inc. 1982 ATP.Alanin.Aspartat.Catalysis.Coenzym.DNA.
描述Some years ago one of my students and I reported that the acetate kinase reaction is mediated by a phosphorylated form of the enzyme [R. S. Anthony and L. B. Spector, lBe 245, 6739 (1970)]. The reversible reaction between ATP and acetate to give acetyl phosphate and ADP had hitherto been thought to proceed by direct transfer of a phosphoryl group from A TP to acetate in a single-displacement reaction. But now it became clear that acetate kinase was one of that substantial number of enzymes whose mech­ anism is that of the double displacement. For some reason, I began to wonder about the possibility that all enzymes, like acetate kinase, are double­ displacement enzymes, and do their work by covalent catalysis. For one thing, I could not think of a single instance of an enzyme for which single­ displacement catalysis had been proved, and inquiries on this point among knowledgeable friends elicited the same negative response. Moreover, it was long known that the two other kinds of chemical catalysis~homo­ geneous and heterogeneous~occur through the intermediary formation of a covalent bond between catalyst and reactant. I began to feel confident that chemical catalysis by enzymes mus
出版日期Book 1982
关键词ATP; Alanin; Aspartat; Catalysis; Coenzym; DNA; Enzym; Fructose; Galactose; Glutamat; Glutamin; Isomer; Nucleoti
版次1
doihttps://doi.org/10.1007/978-1-4612-5663-2
isbn_softcover978-1-4612-5665-6
isbn_ebook978-1-4612-5663-2
copyrightSpringer-Verlag New York, Inc. 1982
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Wege ins Erwachsenenalter in Europa,ve a group from the donor and pass it on to the acceptor. Some of the enzymes chosen for exposition have a long-familiar and accepted mode of action, and are included for the sake of completeness. But others are, at the time of writing, frankly controversial, there being no consensus as to their che
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Zwischen Jugend und Erwachsenenalter,joined to its substrate or a fragment thereof. There are two main reasons for believing this. One is that the two other kinds of chemical catalysis—nonenzymic catalysis in solution and heterogeneous catalysis on a solid surface—proceed in just this way. The other reason rests on a substantial body o
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https://doi.org/10.1007/978-3-531-90799-4ps—NAD, flavin, heme, pterin, a metal ion—or a built-in, redox-active disulfide function. These groups engage in the detailed process of electron transport between the donor and acceptor substrates. Mounting evidence upholds the view that the transfer of electrons between the holoenzyme, on the one
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Wege ins Erwachsenenalter in Europa, electron, a proton, a group, or even the whole—of the donor substrate to an acceptor (1). For convenience of classification, however, the Enzyme Commission of the International Union of Biochemistry has sorted the enzymes into six major classes, only one of which is officially termed “transferases”
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