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Titlebook: Copper-Catalyzed Multi-Component Reactions; Synthesis of Nitroge Yusuke Ohta Book 2011 Springer-Verlag Berlin Heidelberg 2011 atom economy.

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Conclusions,anched substituent was produced with moderate ee values. This indole formation was applicable to the synthesis of indole-fused polycyclic compounds via palladium-catalyzed C–H functionalization at 3-position of indole. Synthetic application to calindol, benzo[.][1,2]thiazines, and indene was also conducted.
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Construction of 2-(Aminomethyl)indoles Through Copper-Catalyzed Domino Three-Component Coupling and g this domino reaction and C–H functionalization at the indole C-3 position, polycyclic indoles were readily synthesized. Construction of benzo[e][1,2]thiazine and indene motifs by the reaction of sulfonamide and malonate congeners is also presented.
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Book 2011e first example of a three-component indole formation without producing salts as a byproduct. Based on this reaction, a copper-catalyzed synthesis of 3-(aminomethyl)isoquinoline was accomplished which represents an unprecedented isoquinoline synthesis through a four-component coupling reaction. Foll
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Facile Synthesis of 1,2,3,4-Tetrahydro-β-Carbolines by One-Pot Domino Three-Component Indole Formatiino three-component coupling-cyclization using an appropriate ethynylaniline, aldehyde, and a secondary amine, treatment with .-BuOK/hexane or MsOH afforded the desired tetrahydro-β-carboline derivatives in moderate to good yields.
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Copper-Catalyzed Multi-Component Reactions978-3-642-15473-7Series ISSN 2190-5053 Series E-ISSN 2190-5061
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