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Titlebook: Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity; Frederick C. Kauffman (Director) Book 1994 Springer-Verlag Berlin Hei

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书目名称Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
编辑Frederick C. Kauffman (Director)
视频videohttp://file.papertrans.cn/236/235569/235569.mp4
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity;  Frederick C. Kauffman (Director) Book 1994 Springer-Verlag Berlin Hei
描述Advances in molecular biology describing important enzyme systems involved in drug conjugation and deconjugation reactions and recent work indicating the importance of drug and xenobiotic conjugates as transport forms of biologically active compounds are reviewed comprehensively. Part One describes molecular events associated with the expression and regulation of transferases and hydrolases involved in Phase II drug conjugation and deconjugation. Part Two deals with the regulation of Phase II conjugation, and Part Three reviews critically the importance of drug conjugates in pharmacology and toxicology. This volume is an up-to-date source of information on this topic and will be of broad interest to pharmacologists and toxicologists.
出版日期Book 1994
关键词Drug conjugates; Konjugation; Stoffwechsel; Transferasen; acyl-linked conjugates; conjugate; enzymes; hydro
版次1
doihttps://doi.org/10.1007/978-3-642-78429-3
isbn_softcover978-3-642-78431-6
isbn_ebook978-3-642-78429-3Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 1994
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发表于 2025-3-21 20:57:46 | 显示全部楼层
https://doi.org/10.1007/978-3-642-78429-3Drug conjugates; Konjugation; Stoffwechsel; Transferasen; acyl-linked conjugates; conjugate; enzymes; hydro
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978-3-642-78431-6Springer-Verlag Berlin Heidelberg 1994
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Finanzielle UnternehmensführungGlucuronidation is a major detoxication pathway in all vertebrates examined, from the most primitive (fish; C. et al. 1991) to the most evolved (man; D. 1980) and accounts for most of the detoxified material in bile and urine (D. 1980).
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The Uridine Diphosphate Glucuronosyltransferase Multigene Family: Function and RegulationGlucuronidation is a major detoxication pathway in all vertebrates examined, from the most primitive (fish; C. et al. 1991) to the most evolved (man; D. 1980) and accounts for most of the detoxified material in bile and urine (D. 1980).
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Die Kapitalflussrechnung nach IFRSug (reviewed in W. 1987). Isoniazid was a remarkably effective therapeutic agent, but, despite its effectiveness, a high proportion (3.5%–17%) of treated patients developed a devastating, progressive nerve toxicity. Pharmacokinetic studies of isoniazid elimination in twins and in families revealed s
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Der Geldkreislauf des Unternehmensng experimental results have appeared in these areas within the past 3 years. This review includes recent studies on the genetics and molecular mechanisms of glucuronidase subcellular localization, induction of glucuronidase by hormones, a new glucuronidase with unusual catalytic activity and inheri
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