书目名称 | Computing for Comparative Microbial Genomics |
副标题 | Bioinformatics for M |
编辑 | David W. Ussery,Trudy M. Wassenaar,Stefano Borini |
视频video | |
概述 | Teaches computational / bioinformatic methods for comparison of microbial genomes.Contains detailed examples of comparisons at the level of DNA, RNA and protein, in terms of structure and functional a |
丛书名称 | Computational Biology |
图书封面 |  |
描述 | Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on |
出版日期 | Textbook 2009 |
关键词 | Chromosome; DNA; Metagenomics; RNA; bioinformatics; databases; evolution; gene expression; genome; heat map; m |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-84800-255-5 |
isbn_softcover | 978-1-84996-763-1 |
isbn_ebook | 978-1-84800-255-5Series ISSN 1568-2684 Series E-ISSN 2662-2432 |
issn_series | 1568-2684 |
copyright | Springer-Verlag London 2009 |