Titlebook: Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models; Aslak Tveito,Glenn T. Lines Book‘‘‘‘‘‘‘‘ 2016 The

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https://doi.org/10.1007/0-306-47211-2that the channel is non-conducting, but when the channel is inactivated, it is harder to open again than when the channel is in the closed state. This feature is useful in modeling an action potential. In the action potential of a cardiac cell, the upstroke is driven mainly by the sodium current. Wh

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Atoms and Pointwise Multipliers,all parts of a cell. We started by studying the dynamics going on in a single dyad; see Fig. 2.1 The size of one dyad is less than 1/1,000 μm.[3] and we have been concerned with the concentration of calcium ions in this small volume. We have also studied the voltage dynamics in the vicinity of a sin

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Computing Characterizations of Drugs for Ion Channels and Receptors Using Markov Models978-3-319-30030-6Series ISSN 1439-7358 Series E-ISSN 2197-7100

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: What Use is it to a Teacher?,Let us briefly recall the difficulty we want to overcome with the theoretical drug. The difficulty is that in the prototypical reaction defined by the Markov model. the rates may change under various mutations. One case that we have focused on in these notes is CO-mutations where the reaction rate from C to O is increased.

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