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Titlebook: Computational Reconstruction of Missing Data in Biological Research; Feng Bao Book 2021 Tsinghua University Press 2021 Machine Learning.Bi

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书目名称Computational Reconstruction of Missing Data in Biological Research
编辑Feng Bao
视频videohttp://file.papertrans.cn/233/232935/232935.mp4
丛书名称Springer Theses
图书封面Titlebook: Computational Reconstruction of Missing Data in Biological Research;  Feng Bao Book 2021 Tsinghua University Press 2021 Machine Learning.Bi
描述The emerging biotechnologies have significantly advanced the study of biological mechanisms. However, biological data usually contain a great amount of missing information, e.g. missing features, missing labels or missing samples, which greatly limits the extensive usage of the data. In this book, we introduce different types of biological data missing scenarios and propose machine learning models to improve the data analysis, including deep recurrent neural network recovery for feature missings, robust information theoretic learning for label missings and structure-aware rebalancing for minor sample missings. Models in the book cover the fields of imbalance learning, deep learning, recurrent neural network and statistical inference, providing a wide range of references of the integration between artificial intelligence and biology. With simulated and biological datasets, we apply approaches to a variety of biological tasks, including single-cell characterization, genome-wide association studies, medical image segmentations, and quantify the performances in a number of successful metrics..The outline of this book is as follows. In Chapter 2, we introduce the statistical recovery of
出版日期Book 2021
关键词Machine Learning; Biological data analysis; Data imputation; Imbalance learning; Single-cell analysis
版次1
doihttps://doi.org/10.1007/978-981-16-3064-4
isbn_softcover978-981-16-3063-7
isbn_ebook978-981-16-3064-4Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightTsinghua University Press 2021
The information of publication is updating

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Computational Reconstruction of Missing Data in Biological Research
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Fast Computational Recovery of Missing Features for Large-scale Biological Data, focuses on missing gene features in single-cell transcriptomics data. In the rapidly development of single-cell sequencing, the latest technological advances have made it possible to measure the intrinsic activity of single cells on a large scale, and enable to analyze the composition of cells with
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