Titlebook: Computational Neuroscience Models of the Basal Ganglia; V. Srinivasa Chakravarthy,Ahmed A. Moustafa Book 2018 Springer Nature Singapore Pt

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The Molecular, Cellular, and Systems-Level Structure of the Basal Ganglia, STN, GPe, GPi, and the SNr including the various neurotransmitters impacting its function. We start with the system-level connection between cortex and BG and then cover the various cell types, receptors (such as dopaminergic, acetylcholine) present on each of the BG nuclei. The effect of Parkinson

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The Basal Ganglia System as an Engine for Exploration,pathways of the BG produce quite opposite motor manifestations (Albin et al., in Trends Neurosci 12(10):366–375, .). While lesions of the direct pathway (DP), affecting particularly the projections from the striatum to GPi, are associated with hypokinetic disorders (distinguished by a paucity of mov

Mirage

,Synchronization and Exploration in Basal Ganglia—A Spiking Network Model,ural substrate in decision making. In earlier chapters, we had hypothesized earlier that the indirect pathway (IP) of the BG could be the subcortical substrate for exploration. Here, we build a spiking network model to relate exploration to synchrony levels in the BG (which are a neural marker for t

Mirage

,A Basal Ganglia Model of Freezing of Gait in Parkinson’s Disease,a (BG), where there is cessation of locomotion under specific contexts. These contexts could include motor initiation, i.e., when starting movement, passing through narrow passages and corridors, while making a turn and as they are about to reach a destination. We have developed computational models

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马赛克

A Cortico-Basal Ganglia Model to Understand the Neural Dynamics of Targeted Reaching in Normal and model consists of the following components: a two-joint arm model (AM), a layer of motor neurons in the spinal cord (MN), the proprioceptive cortex (PC), the motor cortex (MC), the prefrontal cortex (PFC), and the basal ganglia (BG). The model thus has an outer sensory-motor cortical loop and an in