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Titlebook: Computational Methods in Systems Biology; 13th International C Olivier Roux,Jérémie Bourdon Conference proceedings 2015 Springer Internatio

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978-3-319-23400-7Springer International Publishing Switzerland 2015
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A Genetically Modified Hoare Logic that Identifies the Parameters of a Gene Networkd from biological traces, they play a role similar to programs in the classical Hoare logic. We firstly remind the discrete modelling for genetic networks defined by René Thomas. Then, we define the Hoare/Dijkstra method extended to gene networks, that extracts the weakest precondition on parameter values.
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Conference proceedings 2015ubmissions. The papers cover a wide range of topics in the analysis of biological systems, networks and data such as model checking, stochastic analysis, hybrid systems, circadian clock, time series data, logic programming, and constraints solving ranging from intercellular to multiscale.
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0302-9743 tic analysis, hybrid systems, circadian clock, time series data, logic programming, and constraints solving ranging from intercellular to multiscale.978-3-319-23400-7978-3-319-23401-4Series ISSN 0302-9743 Series E-ISSN 1611-3349
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Conference proceedings 2015ntes, France, in September 2015. The 20 full papers and 2 short papers presented were carefully reviewed and selected from 43 full and 4 short paper submissions. The papers cover a wide range of topics in the analysis of biological systems, networks and data such as model checking, stochastic analys
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Marko Samardzic,Ugljesa Marjanovicbrium, i.e. in a steady state. We prove the correctness of our simplification rules for all contexts that preserve the equilibrium of the eliminated molecules. Finally, we illustrate at a concrete example network from systems biology that our simplification rules may allow to drastically reduce the size of reaction networks in practice.
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