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Titlebook: Computational Methods in Systems Biology; 7th International Co Pierpaolo Degano,Roberto Gorrieri Conference proceedings 2009 Springer-Verla

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Organization and Management Innovationodel as a probabilistic approximation of the ODE dynamics by discretizing the value space and the time domain. We then sample a representative set of trajectories and exploit the discretization and the structure of the signaling pathway to encode these trajectories compactly as a dynamic Bayesian ne
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Successful Management by Motivationmodel, this method enables the computation of a reduced model by iteratively “hiding” regulatory components. To keep a consistent behaviour, the logical rules associated with the targets of each hidden node are actualised to account for the (indirect) effects of its regulators..The construction of r
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Computing Reachable States for Nonlinear Biological Models,ugging biological models. We then develop a novel algorithm for computing reachable states for . systems and report experimental results obtained using a prototype implementation. We believe these results constitute a promising contribution to the analysis of complex models of biological systems.
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978-3-642-03844-0Springer-Verlag Berlin Heidelberg 2009
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https://doi.org/10.1057/978-1-137-58990-3 attempts to directly link biological data with Narrative primitives by suggesting an equivalence relationship between a string (the amino acid sequence) and a process. We outline future challenges in applying this approach more generally.
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