Titlebook: Computational Methods for Three-Dimensional Microscopy Reconstruction; Gabor T. Herman,Joachim Frank Book 2014 Springer Science+Business M

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Book 2014ve way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies

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https://doi.org/10.1007/978-1-4612-0235-6ications of standards in the field of three-dimensional electron microscopy. This is the case of EMX in which affine transformations have been adopted as the means to communicate geometrical information.

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https://doi.org/10.1007/978-1-4419-1767-6se ratio and the presence of contaminants. We present a novel machine-learning algorithm that overcomes these problems. The performance of the algorithm is demonstrated with electron micrographs of ribosomes.

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Substance Abuse and Psychiatric Problems, local resolution estimation demonstrates the extent to which resolution can be anisotropic and pinpoints regions of higher heterogeneity or structural flexibility. This study also shows an example of misuse of spatial frequency filters leading to overfitting of the data and the artifacts that can be observed in the resulting density map.

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Interchanging Geometry Conventions in 3DEM: Mathematical Context for the Development of Standards,ications of standards in the field of three-dimensional electron microscopy. This is the case of EMX in which affine transformations have been adopted as the means to communicate geometrical information.

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Using Component Trees to Explore Biological Structures,used to obtain an image of the specimen and the resolution of that image. We present various scenarios in which component trees can help in the exploration of the structure of a macromolecular complex. In addition, we discuss ideas for a docking methodology that uses component trees.

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