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Titlebook: Complement Activation in Malaria Immunity and Pathogenesis; José A. Stoute Book 2018 Springer International Publishing AG, part of Springe

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Complement Evasion Mechanisms of the Human Pathogen ,, provides a brief overview of complement evasion strategies employed by blood-stage malaria parasites and highlights the importance of understanding the complex interplay between complement and parasite infection.
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Role of Complement in Severe Malarial Anemia,netic studies have not revealed any strong associations between CR1 polymorphisms and severe malarial anemia. Further genetic association studies between polymorphisms of the complement genes and susceptibility to SMA are needed to identify additional potential therapeutic targets.
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Role of Complement in Cerebral Malaria,eficient in the receptors for C3a and C5a are fully susceptible to ECM. These results implicated C5b and the membrane attack complex (MAC) as the drivers of ECM pathogenesis. Indeed, treatment with anti-C9 antibody reduced mortality in ECM. The detection of C5a in the serum of C3-deficient mice sugg
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Complement and Malaria in Pregnancy, low birth weight, and neurodevelopmental deficits. Together, these data indicate a critical role for complement in the pathophysiology of malaria in pregnancy and suggest that it is a target for drugs to reduce malaria-mediated adverse pregnancy outcomes.
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Complement Activation in Malaria Immunity and Pathogenesis
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Christoph Lindinger,Nora Zeiselnetic studies have not revealed any strong associations between CR1 polymorphisms and severe malarial anemia. Further genetic association studies between polymorphisms of the complement genes and susceptibility to SMA are needed to identify additional potential therapeutic targets.
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