书目名称 | Coarse-Grained Modelling of DNA and DNA Self-Assembly |
编辑 | Thomas E. Ouldridge |
视频video | http://file.papertrans.cn/229/228716/228716.mp4 |
概述 | Nominated as an outstanding contribution by the University of Oxford.Presents a novel model with remarkable explanatory power.Holds important potential for dynamic DNA nanotechnology.Includes suppleme |
丛书名称 | Springer Theses |
图书封面 |  |
描述 | This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. |
出版日期 | Book 2012 |
关键词 | Biological Motors; Coarse Grained Molecular Simulation; DNA Nanotechnology; DNA Tweezers; DNA Walker; Mol |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-30517-7 |
isbn_softcover | 978-3-642-43652-9 |
isbn_ebook | 978-3-642-30517-7Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
issn_series | 2190-5053 |
copyright | Springer-Verlag Berlin Heidelberg 2012 |