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Titlebook: Coarse-Grained Modelling of DNA and DNA Self-Assembly; Thomas E. Ouldridge Book 2012 Springer-Verlag Berlin Heidelberg 2012 Biological Mot

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书目名称Coarse-Grained Modelling of DNA and DNA Self-Assembly
编辑Thomas E. Ouldridge
视频video
概述Nominated as an outstanding contribution by the University of Oxford.Presents a novel model with remarkable explanatory power.Holds important potential for dynamic DNA nanotechnology.Includes suppleme
丛书名称Springer Theses
图书封面Titlebook: Coarse-Grained Modelling of DNA and DNA Self-Assembly;  Thomas E. Ouldridge Book 2012 Springer-Verlag Berlin Heidelberg 2012 Biological Mot
描述This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology.
出版日期Book 2012
关键词Biological Motors; Coarse Grained Molecular Simulation; DNA Nanotechnology; DNA Tweezers; DNA Walker; Mol
版次1
doihttps://doi.org/10.1007/978-3-642-30517-7
isbn_softcover978-3-642-43652-9
isbn_ebook978-3-642-30517-7Series ISSN 2190-5053 Series E-ISSN 2190-5061
issn_series 2190-5053
copyrightSpringer-Verlag Berlin Heidelberg 2012
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Screenwriting for Virtual Reality upted as the temperature increases. The literature is divided on both the nature of the attraction and the thermodynamics of the transition. The relative contributions of van der Waals, induced dipole, hydrophobic and permanent polar/electrostatic interactions remain unclear.
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Introduction,nges accompanying the formation of B-DNA duplexes from single strands. This process, known as hybridization, is a vital component of the fast-growing field of DNA nanotechnology, as well as being relevant to a wide range of biological systems.
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Thermodynamic Properties of Model DNA,upted as the temperature increases. The literature is divided on both the nature of the attraction and the thermodynamics of the transition. The relative contributions of van der Waals, induced dipole, hydrophobic and permanent polar/electrostatic interactions remain unclear.
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978-3-642-43652-9Springer-Verlag Berlin Heidelberg 2012
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