书目名称 | Coarse-Grained Modelling of DNA and DNA Self-Assembly | 编辑 | Thomas E. Ouldridge | 视频video | | 概述 | Nominated as an outstanding contribution by the University of Oxford.Presents a novel model with remarkable explanatory power.Holds important potential for dynamic DNA nanotechnology.Includes suppleme | 丛书名称 | Springer Theses | 图书封面 |  | 描述 | This thesis presents a novel coarse-grained model of DNA, in which bases are represented as rigid nucleotides. The model is shown to quantitatively reproduce many phenomena, including elastic properties of the double-stranded state, hairpin formation in single strands and hybridization of pairs of strands to form duplexes, the first time such a wide range of properties has been captured by a coarse-grained model. The scope and potential of the model is demonstrated by simulating DNA tweezers, an iconic nanodevice, and a two-footed DNA walker — the first time that coarse-grained modelling has been applied to dynamic DNA nanotechnology. | 出版日期 | Book 2012 | 关键词 | Biological Motors; Coarse Grained Molecular Simulation; DNA Nanotechnology; DNA Tweezers; DNA Walker; Mol | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-30517-7 | isbn_softcover | 978-3-642-43652-9 | isbn_ebook | 978-3-642-30517-7Series ISSN 2190-5053 Series E-ISSN 2190-5061 | issn_series | 2190-5053 | copyright | Springer-Verlag Berlin Heidelberg 2012 |
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