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Titlebook: Clinical Tests of Respiratory Function; G. J. Gibson Textbook 1984Latest edition Macmillan Publishers Limited 1984 function.internal medic

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Renal diseases,fter taking account of these effects, there remain in many patients abnormalities of the CO Diffusing Capacity — usually a reduction but occasionally, in the specific case of Goodpasture’s syndrome, an increase.
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https://doi.org/10.1007/978-3-658-08407-3uter program.. In an individual patient, however, the attribution of breathlessness to the heart or the lungs or both remains a common and difficult problem, especially since some of the functional changes in patients with cardiac disease resemble those of primary lung or airway disease.
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Tests of ventilatory control,ercostal and phrenic nerves; and the effector ‘organ’, the respiratory muscles, whose efficiency in adjusting ventilation to metabolic requirements is influenced by the mechanical and gas-exchanging properties of the lungs.
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Diseases of pleura and chest wall,erefore, often contribute to the results of conventional tests. In general the integrity of the alveolar-capillary membrane is retained but the impairment of full expansion of the lung may lead to some reduction of the CO Diffusing Capacity and to a .CO which is typically high normal or frankly increased (see section 3.2).
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https://doi.org/10.1007/978-3-642-51349-7least three estimates should be obtained wherever possible, so that their reproducibility can be assessed and occasional ‘rogues’ discarded. The variability of results obtained on different occasions is often a good guide to their accuracy but the influence of true physiological or pathological variation also needs to be borne in mind.
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