Titlebook: Clinical Benefits of Leukodepleted Blood Products; Joseph Sweeney,Andrew Heaton Book 1995 Springer-Verlag Berlin Heidelberg 1995 attention

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Ravinder S. Dahiya,Maurizio Vallehese products and a discussion of the proved and potential clinical benefits derived from the transfusion of these products in lieu of conventional white blood cell containing components. The advantages documented for the use of these products include a reduced incidence of nonhemolytic febrile tran

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Anthony J. Costello,Fairleigh Reeveshas been available for many decades, the recent development of filters capable of achieving a 3–4 log reduction in white cell content has stimulated interest in the use of these filters to prevent adverse effects such as HLA sensitization and CMV transfusion..Blood filters are classified as screen o

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Anthony J. Costello,Fairleigh Reeveswhole blood donation. These white cells are predominantly granulocytes. Granulocytes may be metabolically active and release oxidant radicals. They certainly degenerate rapidly on storage, releasing proteolytic enzymes. Such substances may damage the red cell membrane, resulting in accelerated glyco

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Jean V. Joseph M.D., M.B.A.,Ahmed Ghazi M.D.ransfusion support. A number of recent studies have provided information about the role of the passenger leukocytes that remain in blood products and how these initiate antibody development by participating in the immunization process. Small numbers of leukocytes, 10.–10., may induce antibody develo

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Trushar Patel M.D.,Ketan K. Badani M.D.of transfusion on cellular immune function. This includes down-regulation of effector cells, activation of latent viral infection, and the prolonged circulation of donor immunocompetent cells, as seen in graft-versus-host disease (GVHD)..In addition, there are now extensive data showing conclusively

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Surgical Anatomy of Kidneys and Adrenalsoccur in open heart surgery and result in considerable morbidity. The mechanism of RI is thought to be an interaction between activated leukocytes, and reperfused endothelium, resulting in the release of variety of substances, such as activated oxygen species or proteolytic enzymes, with potential f