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Titlebook: Circadian Clock in Brain Health and Disease; Olivia Engmann,Marco Brancaccio Book 2021 The Editor(s) (if applicable) and The Author(s), un

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Palgrave Studies in Languages at Warr regulator of biological clocks, the suprachiasmatic nucleus (SCN). Substantial oscillatory activity in the brain’s reward system is regulated by dopamine. While light serves as a primary time-giver (.) of physiological clocks and synchronizes biological rhythms in 24-h cycles, nonphotic stimuli ha
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Palgrave Studies in Languages at War. Here, we review how circadian clock transcription factors regulate neuromodulator systems such as histamine, dopamine, and orexin that promote arousal. These circadian transcription factors all lead to repression of the histamine, dopamine, and orexin systems during the sleep period, so ensuring i
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Palgrave Studies in Languages at Warcircadian timekeeping in mammals, were found to undergo morphological and protein expression changes in a cyclic 24-h pattern, suggesting that glia could harbour circadian timekeeping mechanisms and that neuron–glia interactions could play a part in the daily organisation of rhythms of physiology an
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Palgrave Studies in Languages at Wary and hyperactivity. Similar to many other neuropsychiatric conditions, ADHD is associated with very high levels of sleep disturbance. However, it is not clear whether such sleep disturbances are precursors to, or symptoms of, ADHD. Neither is it clear through which mechanisms sleep and ADHD are lin
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Palgrave Studies in Languages at Warct on drug-taking behavior. This book chapter explores the interplay between drugs and the circadian system. The reader will be introduced to the main classes of psychoactive drugs and the role they play in circadian pathways and behaviors. The importance of circadian interventions on drug-taking an
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Literature Review and Research Questions,rm this, implicating a role for circadian rhythm disruptions in mood disorder pathophysiology. Molecular clock gene mutations are associated with increased risk of mood disorder diagnosis and/or severity of symptoms, and mouse models of clock gene mutations have abnormal mood-related behaviors. The
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Regional Mortality Differences in Germanyimpairments have typically been thought of as sequelae of underlying neurodegenerative processes in sleep-wake cycle regulating brain regions, including the brainstem, hypothalamus, and basal forebrain, emerging evidence now indicates that sleep deficits may also act as pathophysiological drivers of
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978-3-030-81149-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
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